NOVEL METHYLDOPA EXTENDED RELEASE MATRIX TABLETS
- Publish Date: 2017-03-08
Research Abstract:
The objective of the present study was to develop extended release (ER) matrix tablets of methyldopa using hydrophilic hydroxypropyl methylcellulose (HPMC) alone and in combination with hydrophobic ethylcellulose (EC), and to study the effect of some formulation variables (HPMC viscosity grade and combination with hydrophobic polymer in different ratio) on the properties of prepared tablets.
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