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This paper presents a new method for separating Rhenium, Molybdenum, Vanadium and Tungsten ions on a thin layer of Perlite using the thin layer -electro-chromatography method. This method is based on the combination between chromatographic forces and electric forces by applying different voltages on the separation plate for different times using several electrolytes as different mobile phase concentrations, at different applying field duarations on the process. This method also shows the possibility of using Perlite as a thin layer in this kind of separation process, which can apply in the separation of other types of biochemistry and inorganic ions This relatively simple method is cost effective.

his study was conducted to evaluate the use of plasma rich in growth factors (PRGFs) with immediate implant placement in periodontally compromised extraction sites. Fifteen patients with chronic periodontitis were included. Each received two implants placed immediately after extraction in the anterior region of the mandible. One of the two implants was treated with PRGFs (group I), while the other was not and served as a control (group II). Implant survival, plaque index (PI), bleeding index (BI), probing pocket depth (PPD), and marginal bone loss (MBL) were evaluated for both groups. Complete soft tissue healing occurred in all patients and all implants were successfully osseointegrated over 12 months.

Biomechanical assessment of orbital fractures using patient-specific models and clinical matching

Orbital wall fractures consider one of the most common fractures in the maxillofacial trauma. These fractures caused by two mechanisms, the buckling mechanism and hydraulic mechanism. This study aims to compare between the two mechanisms in terms of intensity and extension using the finite elements method.

Material and methods

Three-dimensional model of the skull was generated using computed tomography data of young male patient. Virtual loads were applied on the eyeball and the infra-orbital rim separately. Von Mises stresses were examined in each simulation.

Results

The simulation predicted fractures on the infra-orbital rim and orbital floor when simulating the hydraulic mechanism, and on the orbital floor and mesial wall when simulating the buckling mechanism.

ScienceDirect

This paper presents a new method for separating Rhenium, Molybdenum, Vanadium and Tungsten ions on a thin layer of Perlite using the thin layer -electro-chromatography method. This method is based on the combination between chromatographic forces and electric forces by applying different voltages on the separation plate for different times using several electrolytes as different mobile phase concentrations, at different applying field duarations on the process. This method also shows the possibility of using Perlite as a thin layer in this kind of separation process, which can apply in the separation of other types of biochemistry and inorganic ions This relatively simple method is cost effective.

This study is conducted to evaluate the antimicrobial activity of one extract of Styrax officinalis L envelopes of berries plant belonging to the Styracae family collected from the coastal area surrounding the city of Lattakia, Syria. Many efforts have been made to discover a new antimicrobial from a variety of sources such as micro- organisms, animals and plants. One such source is Folk medicine. Systematic screening of them may result in the discovery of a new effective compound. These extracts are prepared with polar solvent (methanol) by the steeping extraction method. 

VITAMIN D DEFICIENCY AND DEPRESSIVE DISORDERS: REVIEW STUDY OF PROBABLE RELATIONSHIP

Vitamin D deficiency is evident in many parts of the world, even in the sunnier regions, for a variety of reasons. Recently, vitamin D has been reported in many scientific researchers as an important factor that may have significant health benefits in the prevention and the treatment of many chronic illnesses such as depression. According to the Global Burden of Disease Study, depression is one of the world's leading causes of disability and affects 350 million people in all communities across the world. 

International Journal of Pharmacy and Pharmaceutical Sciences

A series of 3-carboxylic derivatives of disubstituted 1,5-benzodiazepines (5–9) was synthesized by hetero-cyclisation from 1,2-diaminobenzene (1) with dibenzoylmethane (2) followed by bromination on position 3 and by introduction of the carboxylic group or introduction of the malonic moiety. Reduction of the hetero-cycle gave the perhydro derivative diethyl (2,4-diphenyl-1,2,4,5-tetrahydro-3H-1,5-benzodiazepin-3-yl)malonate (9).

To evaluate the in vitro interaction between different extracts of Thymbra spicata L. and certain antimicrobial drugs of different mechanisms, including ampicillin, cefotaxime, amikacin and ciprofloxacin.

There are several generics of metformin hydrochloride tablets available within the drug delivery system globally. Numerous brands of Metformin tablets (850mg) are available in the Syrian drug market. The objective of this study is to determine the biopharmaceutical and chemical equivalence of five brands of Metformin tablets marketed in Syria.

Assessment of physicochemical properties of furosemide (40mg) tablets marketed in Syria

There are several generics of furosemide tablets available within the drug delivery system globally. Numerous brands of furosemide (40 mg) are available in the Syrian drug market. The objective of this study is to determine the biopharmaceutical and chemical equivalence of three brands of furosemide tablets marketed in Syria.

Journal of Chemical and Pharmaceutical Sciences

Continued Progress towards Elimination of Lymphatic Filariasis

Lymphatic filariasis is one of the most debilitating neglected tropical diseases (NTDs). It causes many infectious diseases leading to physical disabled, mental, social and financial losses. Since the year 2000, the World Health Organization (WHO) has launched a campaign to eliminate lymphatic filariasis, and significant achievements have been made in limiting the prevalence of disease in endemic regions. We will highlight certain points on Global Programme to Eliminate Lymphatic Filariasis (GPELF) and review the possibility of vaccine development against lymphatic filariasis in humans.

Journal of Chemical and Pharmaceutical Sciences

Vitamin D: Structure and Physiological Importance

Vitamin D is a steroid hormone. Our body can synthesize vitamin D upon exposure to sunlight unlike all other vitamins, or obtain it from fortified foods or dietary supplements. Interesting aspects have been clarified lately about this vitamin metabolism in the living cell and its different physiological roles concerning mineral and bone homeostasis, cardiovascular function, renal diseases, cancer and immune system modulation. This review summarizes the impact of vitamin D and vitamin D metabolites (25-hydroxy vitamin D [25(OH)D] and 1,25-dihydroxy vitamin D [1,25(OH)2D]) in the human body

Journal of Chemical and Pharmaceutical Sciences

Anthocyanin pigments: Structure and biological importance

Anthocyanins are coloured water-soluble pigments representing one of the major subclasses of compounds. They rarely exist in nature as free aglycons, instead, they attach to one or more sugar moieties. Anthocyanins are found within different plant organs; flowers, leaves, fruits, roots, tubers and grains. They appear in different attractive colours depending on their structure, pH, and other factors. These compounds gained a lot of attention in the last few years as food colourants replacing chemical dyes, besides their role in enhancing plant tolerance against many abiotic stresses such as salinity, drought, excessive light, ultraviolet radiation and cold stress. Besides, previous studies demonstrated the importance of anthocyanins in human health and their protective properties against chronic diseases.

Journal of Chemical and Pharmaceutical Sciences

Study In Epidemiology of Cancer In Syrian Arab Republic Between 2008-2012

The study included an epidemiological survey of cancer cases in the Syrian Arab Republic for the period between 2008-2012. The study was conducted according to international standards established by the International Agency for Research on Cancer (IARC) and the International Association of Cancer Records (IACR). The data were collected and classified according to age, gender, place of incidence and city of residence. Then they were scheduled, graphically illustrated, and statistically analyzed. 46447 new cancer cases were reported during the period of study; 24240 cases among males, 22207 cases among females and 2008 cases between children (<15 years old). The data showed an increase in the new reported cases between 2008 and 2010, and that increment was followed by a decline in the total reported cases until 2012. The survey indicated that breast cancer was the most common type of cancer among females,

British Journal of Medical and Health Research

SARS-COV-2 Pandemic in Syria: Symptoms and Treatments

SARS-CoV-2 has caused global pandemic that resulted in a dramatic loss of human life worldwide. The first human case was reported in December 2019 in China, and while the first case in Syria was confirmed on March 2020. By July 1st, 2021, 25551 cases were reported in Syria with 1879 deaths. The most common symptoms of covid-19 are fever, dry cough, and shortness of breath. Some patients may endure from musculoskeletal, gastrointestinal and dermatologic symptoms. Many drugs (including antibiotics, corticosteroids, antiviral and Immunomodulatory drugs) have been evaluated and recommended to be used in COVID-19 treatment, resulting in clinical recovery.

British Journal of Medical and Health Research

Societal Usage Of Antibiotics In The Syrian Coastal Region During 2021

This study is based on an electronic questionnaire about the use of antibiotics. It investigates the knowledge about antibiotics and their resistance among the Syrian coastal people. 639 individuals responded to the questionnaire. The results show that there is fairly good information about those drugs. Yet, there is much to be done to spread the awareness in the whole community, especially with regards to enact laws that prohibit antibiotics purchase without a prescription. Doctors on the other hand, should give antibiotics only on necessity. People also have to be well educated about antibiotics resistance, which is an inevitable consequence to the misuse of those drugs.

British Journal of Medical and Health Research

COVID-19 INCIDENCES AND SYMPTOMS AMONG CHILDREN

COVID-19 is an illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to beta-coronaviruses. SARS-CoV-2 has caused a pandemic since it was reported in December 2019 in Wuhan, China. The data about the severity of this viral infection in children increased gradually with the appearance of the new variants, but they are still limited compared to the data of adults. Generally, Children with COVID-19 are asymptomatic or have mild symptoms. The most common symptoms include fever, headache, cough, rhinorrhea, sore throat, myalgias, fatigue and gastrointestinal manifestations.

WORLD JOURNAL OF PHARMACEUTICAL AND MEDICAL RESEARCH

Listeria monocytogenes: Mechanisms of Pathogenesis and Antimicrobial Resistance

Listeria monocytogenes is nonspore-forming, gram-positive rods, it is a widespread bacterium; it can survive for a long time in different environments such as food, soil, water, and feces causing adverse health impacts in both animals and humans. Because of its pathogenesis mechanism combined with its ubiquity, It's considereda serious concern. Invasive listeriosis could be without symptoms until 1 to 4 weeks after infection. It causes serious complications especially in pregnant women, newborn babies, and people with weakened immunity if left untreated. An example of the outbreak in South Africa in January 2018, which resulted in 180 deaths.Attention is conferred on L.monocytogene from being able to adapt to many types of stresses. Moreover, it can activate specific genes during the life cycle allowing it to replicate within many host cell types during its infection. In our review, we will highlight the pathogenicity

Bulletin of Pharmaceutical Sciences. Assiut

Monkeypox: Facts about the Disease

Monkeypox is a zoonotic disease caused by the monkeypox virus of the genus Orthopoxvirus genus and Poxiviridae family. Many animal species, including rodents and monkeys, can transmit the virus. However, the natural reservoir is unknown yet. It can be transmitted to humans via close contact with infected animal or person, or contaminated materials. Monkeypox virus was first detected in 1958 among cynomolgus monkey’s colony in Denmark. The first human case of monkeypox was reported in September 1970 in a 9-month-old child with smallpox-like vesicular skin lesions. This virus usually affects humans and animals living in Central and West Africa, yet it led to several outbreaks previously out of Africa since its discovery. Since 7 May 2022, monkeypox started to appear again in non-endemic countries. By 29 July 2022 at 9:00 PM (GMT), 22485 confirmed cases were recorded worldwide. This review

Bulletin of Pharmaceutical Sciences. Assiut

The purpose of this paper is to investigate the set of ε − optimal solutions to optimization problems from a metrical point of view, and generalize some results in literature that are dealing from a topological point of view. Precisely, we show that the sequence ( ) n f is epigraphical distance convergent to f if and only if for each ε > 0 , the sequence of sets (ε −arg min f n ) is epigraphical distance convergent to (ε −arg min f ) . An analogous result holds for ε − subdifferentials of convex lower semi-continuous functions defined on a Banch space and also for ε − projctions of a point to convex closed subset in X .

Fatigue Loading Effect in Custom-Made All-on-4 Implants System: A 3D Finite Elements Analysis

Objectives

This study aims to evaluate the fatigue stress around custom-made all-on-4 implants system to find out which type of implants have a better performance under different graded multidirectional occlusal forces.

Material and methods

3D normal and implanted models simulating the “All-on-4” concept were created and analyzed under three different conditions of occlusal loadings. Two types of static and fatigue were applied. Stress distribution was analyzed based on von Mises and Goodman theories in ANSYS environment in addition to the safety factor. Statistical tests were performed to assess the significance of the results as well as the reproducibility of the results.

sciencedirect

Bio-Numerical Analysis of the Human Ankle-Foot Model Corresponding to Neutral Standing Condition

In this analytical study, tomography images were imported in DICOM format, after that, the object was exported in the form of three-dimensional structures in STL file format to define and assemble the structures. After that, the computer simulation on numerical model was done. One-way Analysis of variance (ANOVA) test was performed, and a threshold (p&lt;0.05) was used to indicate the significance of results.

J Biomed Phys Eng.

Biomechanical assessment of orbital fractures using patient-specific models and clinical matching

Orbital wall fractures consider one of the most common fractures in the maxillofacial trauma. These fractures caused by two mechanisms, the buckling mechanism and hydraulic mechanism. This study aims to compare between the two mechanisms in terms of intensity and extension using the finite elements method.

Material and methods

Three-dimensional model of the skull was generated using computed tomography data of young male patient. Virtual loads were applied on the eyeball and the infra-orbital rim separately. Von Mises stresses were examined in each simulation.

Results

The simulation predicted fractures on the infra-orbital rim and orbital floor when simulating the hydraulic mechanism, and on the orbital floor and mesial wall when simulating the buckling mechanism.

ScienceDirect

Biomechanical Assessment of the Influence of Inlay/Onlay Design and Material on Stress Distribution in Nonvital Molars

Objectives The aim of this study was to evaluate the influence of inlays/onlays with or without pulp extension from different materials on stress distribution in endodontically treated molars by three-dimensional finite element analysis (3D FEA).

Materials and Methods We used 3D mandibular molar models in this study. The models represented mesio-occluso-distal (MOD) cavities restored by inlays, onlays that covered buccal cusps, and onlays that covered all cusps with pulp extension (modified inlay/onlay) or without pulp extension (conventional inlay/onlay). Three materials (L: lithium disilicate glass-ceramic, P: polymer-infiltrated ceramic network [PICN], and C: nanofilled composite resin) were utilized. A force of 600 N was applied vertically and obliquely. Stress distribution in FEA models was analyzed using the von Mises theory.

European Journal of General Dentistry