Hereditary Ovarian Cancer and Germline Mutations: Review Article

• تاريخ النشر: 2017-10-21

ملخص البحث:

Ovarian cancer is the most lethal gynecologic malignancy, nearly 80% of patients are diagnosed at advanced stage disease (III/IV). Different risk factors are associated with ovarian cancer Obesity, High fat diet, Hormone replacement therapy, and most importantly a family history of breast/ovarian cancer and/or colon cancer. Close relative with ovarian cancer increases a woman’s risk of developing ovarian cancer by ~3 times

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