Assistant Professor
D. Sami Azraq
- Vice Dean for Administrative Affairs
- Faculty Member
Hereditary Ovarian Cancer and Germline Mutations: Review Article
Journal of Genetics and Genetic Engineering21 - October - 2017
Ovarian cancer is the most lethal gynecologic malignancy, nearly 80% of patients are diagnosed at advanced stage disease (III/IV). Different risk factors are associated with ovarian cancer Obesity, High fat diet, Hormone replacement therapy, and most importantly a family history of breast/ovarian cancer and/or colon cancer. Close relative with ovarian cancer increases a woman’s risk of developing ovarian cancer by ~3 times
The Detection of HER2 Gene Amplification in Breast Cancer by upQMPSF
Journal of Genetics and Genetic Engineering22 - September - 2017
The amplification of human epidermal growth factor receptor 2 (HER2) gene in breast cancer identifies patients eligible for Trastuzumab therapy. immunohistochemistry (IHC) and/or fluorescent in situ hybridization (FISH) are the only FDA approved techniques for evaluating HER2 status. However, Interobserver variability is still a dilemma
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