مدرس سابق
D. Osama Mansour
- مدرس سابق
Orally Disintegration Tablets – Patient Friendly Tablets
International Journal of Pharmaceutical Sciences Review and Research / 30 - April - 2015
It is a worldwide known fact that patient compliance is one of the most crucial key factors in recovery and healing. Occasionally, hard-to-swallow tablets are one of the barriers against patient compliance. Hence, pharmaceutical industry has spawned many trials to create and develop new dosage forms for known drugs in order to make them much easier to be taken so that patients positively enjoy the experience. However, one of the most important dosage forms which gained a considerable attention of researchers and pharmaceutical industrialists over the last decades is Orally Disintegrating Tablets (ODTs) which disintegrate in mouth rapidly, usually within a matter of seconds, when placed upon the tongue without the need for water.
Download FileScreening of Antibacterial Activity In vitro of Arum maculatum L. Leaves Extracts
International Journal of Pharmaceutical Sciences Review and Research / 5 - December - 2015
This study is conducted to evaluate the antimicrobial activity of one extract of Styrax officinalis L envelopes of berries plant belonging to the Styracae family collected from the coastal area surrounding the city of Lattakia, Syria. Many efforts have been made to discover a new antimicrobial from a variety of sources such as micro- organisms, animals and plants. One such source is Folk medicine. Systematic screening of them may result in the discovery of a new effective compound. These extracts are prepared with polar solvent (methanol) by the steeping extraction method.
Download FileSYNTHESIS OF 3-CARBOXYLIC DERVATIVES OF 1, 5- BENZOTHIAZEPINES
WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES / 1 - January - 2018
A series of 3-carboxylic derivatives of disubstituted 1,5-benzodiazepines (5–9) was synthesized by hetero-cyclisation from 1,2-diaminobenzene (1) with dibenzoylmethane (2) followed by bromination on position 3 and by introduction of the carboxylic group or introduction of the malonic moiety. Reduction of the hetero-cycle gave the perhydro derivative diethyl (2,4-diphenyl-1,2,4,5-tetrahydro-3H-1,5-benzodiazepin-3-yl)malonate (9).
Assessment of physicochemical properties of metformin hydrochloride (850mg) tablets marketed in Syria
Journal of Chemical and Pharmaceutical Sciences / 1 - June - 2016
There are several generics of metformin hydrochloride tablets available within the drug delivery system globally. Numerous brands of Metformin tablets (850mg) are available in the Syrian drug market. The objective of this study is to determine the biopharmaceutical and chemical equivalence of five brands of Metformin tablets marketed in Syria.
Download FileAssessment of physicochemical properties of furosemide (40mg) tablets marketed in Syria
Journal of Chemical and Pharmaceutical Sciences / 1 - December - 2016
There are several generics of furosemide tablets available within the drug delivery system globally. Numerous brands of furosemide (40 mg) are available in the Syrian drug market. The objective of this study is to determine the biopharmaceutical and chemical equivalence of three brands of furosemide tablets marketed in Syria.
Download FileComparative Study of Different Formulations of Chlorpheniramine Maleate Orally Disintegrating Tablets
International Journal of Pharmaceutical Sciences Review and Research / 8 - March - 2017
Patient compliance is a key factor in recovery or healing, and hard-to-swallow tablets are one of barriers against patient compliance. The purpose of this study is to formulate and evaluate different formulations of Orally Disintegrating Tablets (ODTs) of Chlorpheniramine Maleate.
Download FileEvaluation of Physical and Chemical Properties of Paracetamol (500mg) Tablets Marketed in Syria
Journal of Chemical and Pharmaceutical Sciences / 8 - March - 2017
Paracetamol is medicine in all country and accessible without a prescription. Many commercial types of paracetamol tablets (500mg) are available in the Syrian drug market. The objective of this article is to evaluate the physicochemical characterizes for five commercial types of paracetamol (500 mg) tablets marketed in Syria. Paracetamol was evaluated for mass uniformity, friability, hardness, content uniformity, and dissolution rate. All the groups complied with the pharmacopieal specifications for mass uniformity and friability tests. Two brands (B, D) passed the USP requirements for content uniformity with values (90-110%) while the remaining groups failed. Three tested groups released more than 80% drug in 30 minutes except group A and group C.
Phytochemical Study of Laurus Nobilis in Syria
Journal of Chemical and Pharmaceutical Sciences / 13 - February - 2019
This study was made to recognize the microscopic formation of Lauraus Nobilis leaves, which were collected from different places from Tartous, Syria. And the results showed: fibres and sclereids, oil cells, vessels, stomata and epidermis. Later, six extracts were obtained by using six different solvents: ethanol, methanol, n-hexan, acetic acid, chlorophorm, dichloromethane, these extracts were used for TLC analysis which showed that the L.nobilis contain: limonien, 1,8 cineol, linalool, terpinol. A part of the extracts were used for the chemical tests by using the suitable reagents that resulted the presence of Flavonoids, Alkolids and Tannins.
Review Study on the Physiological Properties and Chemical Composition of the Laurus nobilis
The Pharmaceutical and Chemical Journal / 29 - April - 2018
The Laurus nobilis is one of the plants of the lauraceae species which has many physiological properties. It is an antimicrobial, antifungal, anti-oxidant and other properties that make laurel oil and its compounds a good and a valuable substance for use in pharmaceuticals and cosmetics, chemically contains many compounds such as: turbines, anthocyanins coumarins and others.
Analytical Methods of Ciprofloxacin and its Combinations Review
Research Journal of Pharmacy and Technology / 1 - May - 2018
Ciprofloxacin is a second generic and an antibiotic generic drug. It is a very popular fluoroquinolone that can treat a number of bacterial infections. The quinolones are family or a group that has activity against both-negative and positive-gram bacteria, when compared to Ciprofloxacin. The first aim of this review is to provide a comprehensive update of analytical methods for determining the Ciprofloxacin and its combinations, binary or triple mixture use of endodontic treatment of primary teeth using a combination of antibacterial drugs. The other aim of this review is to evaluate clinical and radiographic success of the endodontic treatment of infected primary teeth using a combination of ciprofloxacin, metronidazole, minocycline, and clindamycin. Several methods were used in the analytical determination of Ciprofloxacin and its metabolites in human biological fluids (plasma) and in pharmaceutical preparations.
Determination of Clopidogrelbisulphate using Drug Selective Membranes
Research Journal of Pharmacy and Technology / 29 - August - 2018
Newly developed ion selective electrode has been developed for determination of Clopidogrelbisulphate(CLP) in pure form and pharmaceutical preparations. The selective electrode was constructed from Clopidogrel with pairing agent Nesslerreagentin presence of di-n-butyl phthalate (DBP) as the plasticizing solvent mediator.
The Influence of Temperature and Moisture on the Physical and Chemical Properties of Metformin Hydrochloride Tablets (850 mg) Marketed in Syria
International Journal of Pharmacy and Pharmaceutical Sciences / 29 - June - 2018
Stability is an essential factor of quality, safety, and efficacy of a drug product. The objective of this study was to investigate the effect of moisture and temperature on metformin hydrochloride tablets (850 mg) marketed in Syria.
Materials and Methods for cleaning dentures- a review
INTERNATIONAL JOURNAL OF DENTAL CLINICS / 8 - March - 2017
Todays dentists and patients has the awareness that accumulation of plaque on dentures has an impact on patients general health. Patients are willing to learn proper oral hygienic techniques and use of advanced materials for the maintenance of the dentures. Dentists have an obligation to motivate and instruct the patient and provide the means and methods for plaque control. This review paper discuss current materials and methods for cleansing dentures and different ways for maintaining oral hygiene.
Screening of Antibacterial activity in Vitro of Cyclamen hederifolium tubers Extracts
Research Journal of Pharmacy and Technology / 8 - March - 2017
This study was conducted to evaluate the antimicrobial activity of four extracts of Cyclamen hederifolium tubers plant belonging to the Primulaceae (Myrisinaceae) family collected from the coastal surrounding, Lattakia, Syria.
Screening of Antibacterial Activity In vitro of Styrax officinalis L. Covers of Berries Extracts
Research Journal of Pharmacy and Technology / 22 - February - 2016
This study is conducted to evaluate the antimicrobial activity of one extract of Styrax officinalis L envelopes of berries plant belonging to the Styracae family collected from the coastal area surrounding the city of Lattakia, Syria.
