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The following adverse reactions have been observed, but there are not enough data to support an estimate of their frequency.

Cardiovascular System

ventricular arrhythmia (at very high doses)
ectopic beats
tachycardia
anginal pain
palpitation
cardiac conduction abnormalities
widened QRS complex
bradycardia
hypotension
hypertension
vasoconstriction

Respiratory System

dyspnea

Gastrointestinal System

nausea
vomiting

Metabolic/Nutritional System

azotemia

Central Nervous System

headache
anxiety

Dermatological System

piloerection

Other

Gangrene of the extremities has occurred when moderate to high doses were administered for prolonged periods or in patients with occlusive vascular disease receiving low doses of dopamine (dopamine hydrochloride) HCl.

A few cases of peripheral cyanosis have been reported.