The following adverse reactions have been observed, but there are not enough data to support an estimate of their frequency.
ventricular arrhythmia (at very high doses)
cardiac conduction abnormalities
widened QRS complex
Central Nervous System
Gangrene of the extremities has occurred when moderate to high doses were administered for prolonged periods or in patients with occlusive vascular disease receiving low doses of dopamine (dopamine hydrochloride) HCl.
A few cases of peripheral cyanosis have been reported.