Skip to main content

Hypervitaminosis D is characterized by effects on the following organ system:

Renal

Impairment of renal function with polyuria, nocturia, polydipsia, hypercalciuria, reversible azotemia, hypertension, nephrocalcinosis, generalized vascular calcification, or irreversible renal insufficiency which may result in death.

CNS

Mental retardation.

Soft Tissues

Widespread calcification of the soft tissues, including the heart, blood vessels, renal tubules, and lungs.

Skeletal

Bone demineralization (osteoporosis) in adults occurs concomitantly.

Decline in the average rate of linear growth and increased mineralization of bones in infants and children (dwarfism), vague aches, stiffness, and weakness.

Gastrointestinal

Nausea, anorexia, constipation.

Metabolic

Mild acidosis, anemia, weight loss.