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Potential Adverse Reactions to benzonatate (benzonatate softgels) may include: Hypersensitivity reactions including bronchospasm, laryngospasm, cardiovascular collapse possibly related to local anesthesia from chewing or sucking the softgel.

CNS: sedation; headache; dizziness; mental confusion; visual hallucinations.

GI: constipation; nausea; GI upset.

Dermatologic: pruritus; skin eruptions.

Other: nasal congestion; sensation of burning in the eyes; vague 'chilly' sensation; numbness of the chest; hypersensitivity. Rare instances of deliberate or accidental overdose have resulted in death.