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The following local adverse reactions have been reported in connection with the use of Bactroban Ointment (mupirocin) : burning, stinging, or pain in 1.5% of patients; itching in 1% of patients; rash, nausea, erythema, dry skin, tenderness, swelling, contact dermatitis, and increased exudate in less than 1% of patients. Systemic reactions to Bactroban Ointment (mupirocin) have occurred rarely.